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Most Respected Viewers ! its all about the Types/ Risk / Factors / Symptoms / Screening Treatment & Prevention What Is Down Syndrome? Down syndrome (sometimes spelled “Down’s syndrome”) is a genetic abnormality. It is the most common single cause of birth defects in the United States This syndrome occurs because of an extra copy of chromosome 21. Your chromosomes contain your genetic material, & any problems with your chromosomes can cause serious physical and mental health problems Down syndrome causes lifelong developmental delays that can range from moderate to severe. It cannot be cured, but there are options. Down syndrome can be managed with educational interventions, specialized parenting techniques, and community engagement. These all can encourage a person with Down syndrome to develop life skills and social bonds, so that they can live a long (many Down syndrome patients live past the age of 50) and fulfilling life. Causes What Causes Down Syndrome? Down syndrome is e genetic disorder. TO understand how it happens, we first need to understand some basic genetics. In all cases of reproduction, both parents pass their genes on to their children. These genes are carried on chromosomes. When the baby’s cells develop, each cell is supposed to receive 23 pairs of chromosomes. Half of the chromosomes are from the mother and half from the father. In children with Down syndrome, one of the chromosomes does not separate properly. The baby ends up with three copies of chromosome 21 instead of two. This extra chromosome causes problems as the brain and physical features develop. Types Types of Down Syndrome There are three types of Down syndrome: Trisomy 21 Trisomy 21 means there is an extra copy of chromosome 21 in every cell. This is the most common form of Down syndrome. Mosaicism Mosaicism means there is an extra chromosome in some but not all of a child’s cells. Individuals with mosaic Down syndrome tend to have fewer symptoms. Translocation In this condition, children have only an extra part of chromosome 21. There are 46 total chromosomes. However, one of them has an extra piece of chromosome 21 attached. Risk Factors Will My Child Be at Risk for Down Syndrome? Certain parents have a greater risk of giving birth to a child with Down syndrome: women age 35 and older males 50 and older people with a family history of Down’s syndrome people who carry the genetic translocation Symptoms What Are the Symptoms of Down Syndrome? During pregnancy, there are no signs that a child will have Down syndrome. At birth, babies with Down syndrome usually have certain characteristic signs, including: flat facial features small head and ears short neck bulging tongue eyes that slant upward oddly shaped ears poor muscle tone A Down syndrome infant can be born a normal size. However development is twice as slow as for an unaffected child. There is usually some degree of mental retardation, but it is often mild to moderate. Mental and social development delays may mean that the child will have: impulsive behavior poor judgment short attention span slow learning capabilities Medical complications often accompany Down syndrome. These are caused by the extra chromosome. These may include: congenital heart defects hearing loss poor vision cataracts (clouded eyes) hip problems, such as dislocations leukemia chronic constipation sleep apnea (interrupted breathing during sleep) dementia (thought and memory problems) hypothyroidism (low thyroid function) obesity late tooth growth, causing problems with chewing Today, despite the medical and developmental delays, a child born with Down syndrome can live past the age of 50 (Mayo Clinic). Screening Screening for Down Syndrome During Pregnancy Screening is offered as a routine part of prenatal care in the United States. However, it is not required. First Trimester An ultrasound evaluation and blood tests can look for Down syndrome in your fetus. These tests are done between the 10th and 14th week of pregnancy. An ultrasound looks at the back of the baby’s neck, called the nuchal translucency. If there are problems with the baby’s development, more fluid collects in this area. Blood tests looks at the level of pregnancy-associated plasma protein-A (PAPP-A) and human chorionic gonadotropin (HCG). High levels of these proteins suggest a developmental problem. These tests have a higher false-positive rate than tests done at later pregnancy stages. If results are not normal, your doctor may follow up with an amniocentesis. In this test, an amniotic fluid sample is used to confirm the results. Second Trimester An ultrasound and quadruple marker screen (QMS) test can help identify Down syndrome and other neural tube defects. This test is done between 15 and 20 weeks. These tests measures four pregnancy-related factors: human chorionic gonadotropin (HCG) unconjugated estriol alpha-fetoprotein (AFP) inhibin-A If any of these tests are not normal, you will be considered at high risk for birth defects. Additional Prenatal Tests Your doctor may order additional tests to detect Down syndrome in your baby: amniocentesis: Your doctor takes a sample of amniotic fluid to examine the number of chromosomes the baby has. The test is usually done at 15 weeks. It carries a one in 200 miscarriage risk. chorionic villus sampling (CVS): Your doctor will take cells from your placenta to analyze fetal chromosomes. This test is done during the ninth and 14th week of pregnancy. It carries a miscarriage risk of one in 100. percutaneous umbilical blood sampling (PUBS): Your doctor will take blood from the umbilical cord and examine it for chromosomal defects. It is done after the 18th week of pregnancy. It carries an even higher rate of miscarriage, so it is performed only if all other tests are uncertain. Some women choose not to undergo these tests, because of the risk of miscarriage. They would rather risk having a child with Down syndrome than losing the pregnancy. Tests at Birth At birth, your doctor will: perform a physical examination of your baby order a blood test called a karyotype to confirm Down syndrome Treatment Treating Down Syndrome There is no cure for Down syndrome. However, parents can provide early intervention and opportunities to help their child with Down syndrome succeed. Early intervention programs promote a child’s learning. They offer the best chance for success. In these programs, special education teachers and therapists will help your child learn: sensory skills social skills self-help motor skills language and cognitive abilities Children with Down syndrome often meet age-related milestones. However, this may take up to two times longer than for other children. A team of physicians and specialists can help provide medical care and manage the medical complications. Because obesity can be particularly dangerous to the health of children with Down syndrome, it is important to encourage physical activity and avoid high-calorie foods. However, before beginning exercise or sports, the child’s hip, neck, and spine should be examined. It is important to teach children with Down syndrome about being independent and staying safe. Parents should establish a support network in the family and community. Learn as much as possible about your child’s condition. This can help you understand what it means as your child grows and develops. Many people with Down syndrome lead successful lives in their community. They often go to school, hold jobs, and become independent. Prevention Preventing Down Syndrome There is no way to prevent Down syndrome. You may want to speak with a genetic counselor: before having a child, to see if you are at risk if you already have a child with Down syndrome and are considering getting pregnant again Regards from' Oxfordcadets Team J Block Firdos Market Gulberg iii Lahore skype id oxfordcadets g mail oxfordcadets at g mail dot com whatsapp +92 333 4/6/3/3/9/9/0 Get Updates on + 92 342 37 2 5 129

EDCONS Institute Of Business & Technology (Lahore) The IADC RigPass accreditation system is designed to meet two requirements: To identify core elements of safety orientation programs for new rig employees To provide a means of recognizing programs that adhere to those elements RigPass Image SafeLandUSA SafeGulf Completion of an IADC RigPass or IADC RigPass Course-to-Go accredited program confirms that personnel have met basic requirements defined by safety and training professionals in the drilling industry, irrespective of the rig’s location. These programs also satisfy the SafeLandUSA and SafeGulf requirements. IADC RigPass accreditation is open to all drilling and ancillary service contractors, commercial providers, or educational institutions and agencies. Operators and contractors may be confident in the knowledge that every program is subject to review and evaluation by independent parties. Site visits and maintenance of an audit history are key parts of the IADC RigPass system. EDCONS Institute Of Business & Technology (Rawalpindi) 28-B, Sadiqabad Stop, Main Murree Road, Satellite Town, Rawalpindi- Pakistan Tel: Fax: Cell: www.edcons.edu.pk EDCONS Institute of Business & Technology (New Lalazar Campus) 32/D, Jhelum Road, Near Ayub Park, New Lalazar Rawalpindi. Tel: Cell: www.edcons.edu.pk EDCONS Institute Of Business & Technology (Lahore) Flat # 16, 2nd Floor, Abuzar Tower, Main Peco Road,Township,Lahore-Pakistan Tel: Cell: www.edcons.edu.pk

EDCONS Institute Of Business & Technology (Lahore) IOSH Working safely course Everyone at work should have an understanding of why they must ‘work safely’. Working safely brochure cover Working safely is a one-day course for people at any level, in any sector, needing a grounding of health and safety. It focuses on why health and safety is important, and how you can make a real difference to the wellbeing of yourself and others through changing your behaviour. It focuses on best practice rather than legislation, it's suitable for delegates from around the world, and not just those from the UK. The course is a 100% match to the Health and Safety Executive’s ‘Passport’ syllabus. Working safely is recognised as an equivalent to a level 1 award in health and safety in a construction environment. This means that delegates who successfully complete it can apply for a Construction Skills Certification Scheme (CSCS) green Labourer card once they’ve passed the CITB Health, Safety and Environment Operatives Test. Five interactive modules: 1. Introducing working safely 2. Defining hazard and risk 3. Identifying common hazards 4. Improving safety performance 5. Protecting our environment End of course assessments: 1. A 10 question, multiple-choice assessment paper (15 mins) 2. Three hazard spotting exercises (15 mins) When you pass, you’ll be awarded an IOSH Working safely certificate or a credit card-sized IOSH passport card. You can study Working Safely in a classroom or by distance/e-learning. Find an IOSH course. EDCONS Institute Of Business & Technology (Rawalpindi) 28-B, Sadiqabad Stop, Main Murree Road, Satellite Town, Rawalpindi- Pakistan Tel: Fax: Cell: www.edcons.edu.pk EDCONS Institute of Business & Technology (New Lalazar Campus) 32/D, Jhelum Road, Near Ayub Park, New Lalazar Rawalpindi. Tel: Cell: www.edcons.edu.pk EDCONS Institute Of Business & Technology (Lahore) Flat # 16, 2nd Floor, Abuzar Tower, Main Peco Road,Township,Lahore-Pakistan Tel: Cell: www.edcons.edu.pk

EDCONS Institute Of Business & Technology (Lahore) 2. What barriers exist to OHSMS success? Research and consultations with OHS experts identify three kinds of barriers to OHSMS success. These relate primarily to the way that OHSMS are being implemented in Australia. Perhaps because of their increasing popularity, their introduction often occurs under inauspicious circumstances. The barriers are: i. Failure to meet necessary conditions for OHSMS success (by not customising systems to organisational needs, imposition without consultation, weak senior management commitment and poor employee involvement). ii. The inappropriate use of audit tools (where they become an end in themselves, are governed by misplaced management objectives, and are conducted without sound auditor skills, standards and criteria). iii. Application in hostile contexts (small business, precarious employment, contractors and labour hire companies). The evidence from the consultations suggests that many applications of OHSMS are likely to fail for these reasons. One common concern is that OHSMS may then get a bad name as another ‘failed fad’. For this reason it may be necessary to address voluntary means to improve understanding in industry of the proper nature of OHSMS, of the necessary conditions for success (including senior management support and employee involvement), of the existence of a range of types of system for different settings, and the necessity to customise workplace applications. The factors contributing to effective OHSMS and the barriers to effective OHSMS are summarised in the table overleaf. EDCONS Institute Of Business & Technology (Rawalpindi) 28-B, Sadiqabad Stop, Main Murree Road, Satellite Town, Rawalpindi- Pakistan Tel: Fax: Cell: www.edcons.edu.pk EDCONS Institute of Business & Technology (New Lalazar Campus) 32/D, Jhelum Road, Near Ayub Park, New Lalazar Rawalpindi. Tel: Cell: www.edcons.edu.pk EDCONS Institute Of Business & Technology (Lahore) Flat # 16, 2nd Floor, Abuzar Tower, Main Peco Road,Township,Lahore-Pakistan Tel: Cell: www.edcons.edu.pk

IOSH Working safely course Everyone at work should have an understanding of why they must ‘work safely’. Working safely brochure cover Working safely is a one-day course for people at any level, in any sector, needing a grounding of health and safety. It focuses on why health and safety is important, and how you can make a real difference to the wellbeing of yourself and others through changing your behaviour. It focuses on best practice rather than legislation, it's suitable for delegates from around the world, and not just those from the UK. The course is a 100% match to the Health and Safety Executive’s ‘Passport’ syllabus. Working safely is recognised as an equivalent to a level 1 award in health and safety in a construction environment. This means that delegates who successfully complete it can apply for a Construction Skills Certification Scheme (CSCS) green Labourer card once they’ve passed the CITB Health, Safety and Environment Operatives Test. Download our Working safely brochure [PDF 845Kb] Five interactive modules: 1. Introducing working safely 2. Defining hazard and risk 3. Identifying common hazards 4. Improving safety performance 5. Protecting our environment End of course assessments: 1. A 10 question, multiple-choice assessment paper (15 mins) 2. Three hazard spotting exercises (15 mins) When you pass, you’ll be awarded an IOSH Working safely EDCONS Institute Of Business & Technology (Rawalpindi) 28-B, Sadiqabad Stop, Main Murree Road, Satellite Town, Rawalpindi- Pakistan Tel: Fax: Cell: www.edcons.edu.pk EDCONS Institute of Business & Technology (New Lalazar Campus) 32/D, Jhelum Road, Near Ayub Park, New Lalazar Rawalpindi. Tel: Cell: www.edcons.edu.pk EDCONS Institute Of Business & Technology (Lahore) Flat # 16, 2nd Floor, Abuzar Tower, Main Peco Road,Township,Lahore-Pakistan Tel: Cell: www.edcons.edu.pk

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Oxfordcadets Recover Explore & Groom your Slow Learning Child's Natural iQ Skills Talent Parents worried about their child's retardation may contact for more updates and possibilities Respected parents if your child is showing no progress or have less capabilities comparatively to other child' its meant there is some reason behind so to perform some higher mental functions by your such child we must interview him to know his main deficiencies and a solution will come for to recover his capabilities we use to teach in society all special children who are considered having mental retardation & the children with some specific intellectual performance deficiencies we assess them with different means and a stage comes that the same child show an unbelievable output performance we can not expect but the efforts take time to do so and we should also think upon that some problem in the development due to the deficiencies of certain things may be recovered through special food supplements and are recommended for Especially those kids or children under the age of 18 to whom we give/ considered or even called as special child or a child having some specific mental retardation A Child is regarded as mentally slow learning or ret who have iQ score less than seventy % We see that even the people grown up but they behave like a kid around in routine' its meant they don't possess the ability to think like an adult they have a Lack of intellectual & learning functions also and Some of them are even unable to learn a new absorbing or quite easy things easily' can't remember easy lessons & are unable to perform an easy task & even don't possess etiquette to meet new people or close relatives of their family members, they get rid off to attend ceremonies & functions remain dirty & even have no sense to live clean like others, they ever hesitate to work in an organization, they do not want to communicate with others & have no interest to even earn money. Such children have interest in schooling & if they r admitted in some streamline school they even remain unable to possess a good grade at school, to pass the Exms, to solve simple questions, to learn the Life-skill for to survive successfully among others. so observe your child and his habits and if you do think they are showing no developing or progress in leaning we are ever here and feel free to contact us to help you out without any further delay we will show their skills performance better to normal children and with in counted days duration and without a single fee or coin For further queries / Admission or updates And Home Tutors Please feel free to contact us or send message on Skype oxfordcadets or cell no 342 3/7/2/5 /1/2/9 Regards from' Akhtar Hayat ( Ex PAF ) Oxfordcadets' Institute for Slow Learning & Child with iQ Skills Deficiencies ( since 1990 ) Firdos Market J block Gulbrg iii Lahore Whats ap 3 3 3 4 6 -3 3- 9 9 0

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